James Phinney, Design Director of Guild Wars and Guild Wars 2 is interviewed at the 2010 Comic-Con in San Diego about Guild Wars 2.
The game seems to have much better combat and spell animations (which I remember was a criticism by some of my friends concerning the original - it didn't compare favourably with the likes of Diablo II) and what I especially like is the mention of "events" which are probably similar to holiday challenges in the old Guild Wars (i.e. bunch of random people go to an ad-hoc event that has popped up to try and fight the best they can through it. If they work well as a team and succeed, they get rewarded for it).
Once again, no official release date has been confirmed :(.