|WATCH OUT! There's a giant tentacle monster thingy right behind you!|
The reason this one's going to be big is because it's a spiritual successor to the Baldur's Gate games. Yes I know that term "spiritual successor" gets thrown around a lot and sometimes a little too liberally in the case of some games. However from what I've seen so far, it seems that Obsidian Entertainment are the real deal. After all, you have guys on the team that have worked on RPG classics such as Fallout, Icewind Dale and Planescape: Torment while they were part of Black Isle, and Star Wars: Knights of the Old Republic II, Neverwinter Nights 2 and Fallout: New Vegas as Obsidian Entertainment.
These guys are expert craftsmen when it comes to RPGs, even though admittedly several of the earlier ones I played were pretty buggy, but the moral dilemmas you face and the strong characterisation that often resonate in their games usually more than make up for it. If you're into old school D&D CRPGs, I think this is definitely one to look out for.
[LINK: Official Pillars of Eternity website]